The Rare Diseases Clinical Research Consortia (RDCRC) opportunity is a grant issued by the National Institutes of Health aimed at establishing a network for clinical research focused on rare diseases. This initiative seeks to foster collaboration among researchers and institutions to enhance the understanding and treatment of rare diseases through clinical trials. Organizations with expertise in clinical research, particularly those with a focus on rare diseases, are encouraged to apply. The grant allows for the optional inclusion of clinical trials, making it suitable for entities that can manage both research and clinical aspects of rare disease studies.